iii the active database
Lab A: Maintaining the MMS Database
... click Start The compaction utility will make three passes through the directory data The first will verify integrity of your ASN database, the second will compact the ASN database, and the third ... Steps Clear the genlogs file and then stop the MMS Server a Open Services from the Administrative Tools menu b In the Services window, right-click MMS Server, and then click Restart The MMS Server ... Maintaining the MMS Database Exercise Verifying Directory Integrity With the MMS Compaction Utility In this exercise, you will run the MMS compaction utility to compress the database and ensure the integrity...
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Tài liệu Exploring the Northwind Database pptx
... key Note The value for the primary key in each row of a table must be unique In the case of the Customers table, the primary key is the CustomerID column The key icon shown to the left of the CustomerID ... can think of the foreign key as a pointer from the Orders table to the Customers table Often, the table containing the foreign key is known as the child table, and the table with the column referenced ... section Definition of the Customers Table Table 2.4 shows the definition for the columns of the Customers table This table shows the column name, database type, length, and whether the column allows...
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Tài liệu Module 18: Case Study Working with the Foodmart Database ppt
... dimension, and then define the hierarchy containing two levels—year and month At the end of the wizard, clear the Share this dimension with other cubes check box After the dimension appears in the cube ... well as the variance of the two years—1997 and 1998 In addition, users want to evaluate the all the values based on the year in which the stores opened The tables that you will use to build the cube ... Foodmart Database 11 Tip To determine the tables and columns to include in the dimensions, browse the dimension tables either in Analysis Manager or in the database schema presented earlier in the...
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Tài liệu Báo cáo khoa học: Stefin A displaces the occluding loop of cathepsin B only by as much as required to bind to the active site cleft doc
... the inhibitors as well as to the packing constraints of the environment The larger and wider the features of the ligands that compete with the occluding loop for binding to the active site, the ... N-terminus, the active site C29 The C-terminal domain is based on a four-stranded b-barrel fold, contributing H199, the other active site residue The active site cleft is formed at the interface ... human [22] and rat procathepsins B [23] They revealed that, in the zymogen form, the propeptide rather than the occluding loop fills the active site cleft It was shown that the single and double...
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Tài liệu Báo cáo khoa học: Solution structure of hirsutellin A – new insights into the active site and interacting interfaces of ribotoxins docx
... the activity Given the 3D structure of the HtA active site, and the interactions between side chains, we propose that D40, H42, R95 and F126 also form part of it As in other ribotoxins, the active ... the structure of the remaining part is the same in both proteins, including a short segment (N56, C57 and D58) forming a turn of 310 helix (D75, C76 and D77 in a-sarcin) The active site The active ... further than other ribotoxins to become smaller and more economical At the same time, the active site of HtA, as revealed by the 3D structure, shows a different arrangement to that shown by the...
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Tài liệu Báo cáo khoa học: Activation loop 3 and the 170 loop interact in the active conformation of coagulation factor VIIa pdf
... conned to the substrate binding cleft (the 170 loop) in the active site region and the S1 pocket, whereas the intramolecular connections, for instance between the TF-binding region and the active ... in the vicinity of the S1 pocket [11,34], in the rst part of activation loop 3, and in the area of the TF-interactive helix and the 170 loop [8,35], areas that are stabilized by TF [9,25,26] The ... substrate processing These bonds are two of the components of the invisible scaffold supporting the active conformation One bond participates in stabilization of the 170 loop while the other connects...
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Tài liệu Báo cáo khoa học: A tyrosinase with an abnormally high tyrosine hydroxylase/dopa oxidase ratio Role of the seventh histidine and accessibility to the active site docx
... respectively, the amounts of protein (lg) in the TH and DO activity peaks Yields were calculated with the values in parentheses, which are the three most active fractions from the purification ... is at pH These preferred activities of the two PPOs of R solanacearum are opposite to the names assigned to them when the genome of this bacterium was sequenced and the function of these conceptual ... logical according to the mathematical algorithm used for the blast search Score and e values depend on several factors, but mostly the total length of the sequence used for the blast The shorter sequence...
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Tài liệu Using the Python Database API with Red Hat Database docx
... Using the Python Database API with Red Hat Database Getting Ready to Use the Python Database API with Red Hat Database To use the Python Database API, you need the Python interpreter as well as the ... to the database def initialize (): # Connect to the basketball database Use the dsn as the connection # parameter The Python DB-API details the other valid connection # parameters Notify the ... through the process of connecting to a database, inserting Red Hat Using the Python Database API with Red Hat Database Using the Python Database API with Red Hat Database a row, and then disconnecting:...
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Tài liệu The Neo Database – A Technology Introduction (20061123) doc
... on evolutionary software design will put the problems of schema evolution at the top of the agenda in this decade Both the impedance mismatch and the schema evolution problem stem from the relational database' s origin in the early ... puts it, the great majority of the data out there is not structured and [there's] no way in the world you can force people to structure it.”1 Even the major database vendors acknowledge that the relational technology is insufficient ... between nodes. If you have another look at the social network example, you'll see that there's more information in the relationships between nodes than in the nodes themselves. The value of a network is in the connections between the ...
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Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx
... between the base G4 and the sidechain of Asn122 In the second model (Fig 1B) the structure of the hexanucelotide is, on the whole, unchanged and the majority of the interactions that were seen in the ... at the bottom left and the target adenine is at the top of each model The sidechains of RTA are shown in blue (A) Model has the tetraloop bound in the active site of RTA with G4 stacked upon the ... 234 and 235 [9] Of theses residues, only Arg213 is in the vicinity of the active site of RTA In order to establish the role of arginyl residues around the active site of RTA in the binding of rRNA,...
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Tài liệu Báo cáo khoa học: Enlarging the gas access channel to the active site renders the regulatory hydrogenase HupUV of Rhodobacter capsulatus O2 sensitive without affecting its transductory activity docx
... during the activation step of the ready enzyme increases the lag phase without preventing the activation [29] On the other hand, when added to the active enzyme, O2 would react directly with the active ... (probably the HupU subunit) interacts with the N-terminal domain of the histidine kinase HupT to transduce the signal of H2 availability [13] We therefore addressed the question of whether the mutation ... the deeply buried active site [23–25] As both molecular H2 and O2 are hydrophobic gases, they probably use the same access pathway to the hydrogenase active site The amino-acid sequences of the...
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Tài liệu USER’S GUIDE TO THE -IR- DATABASE INDIANA REGISTER — AND — INDIANA ADMINISTRATIVE CODE doc
... the AROC and an electronic copy of the notice to the Publisher The electronic copy received by the Publisher is the document that is posted on the -IR- Database Website Agencies should send their ... attachments to the same e-mail Please make sure the LSA Document number is included either in the file name of the attachments or as part of the text of the documents themselves NOTE: The prohibition ... of the cite, the agency may contact the Publisher with the replacement cites The Publisher will then make the necessary changes It is not necessary to amend an IAC section just to change the...
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Tài liệu Báo cáo khoa học: Site-directed mutagenesis of a loop at the active site of E1 (a2b2) of the pyruvate dehydrogenase complex A possible common sequence motif docx
... properly as a lid for the active site, thereby granting easier access for the cofactor ThDP to its binding site The lower thermal stability of the mutant E1s and the increased Vmax in the DCPIP assay, ... detected by the PDH assay The interaction of E1 (a2b2) with the PSBD was unaffected by any of the mutations in E1a (Fig 4) Therefore, any effects of the mutations on the catalytic activities of the PDH ... with the E1 crystal structures in that the arginine residues corresponding to E1aR282 of the B stearothermophilus E1 are not pointing towards the active site, identified by the C2-carbon of the...
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Tài liệu Báo cáo Y học: The insert within the catalytic domain of tripeptidyl-peptidase II is important for the formation of the active complex potx
... located in the insert within the catalytic domain, close to the catalytic His264, and the proximity to the active site may explain the effect of oligomerization on enzyme activity Even though the exact ... differences in the C-terminal part of the enzyme (Fig 2A) where 13 of 44 amino acids are different Therefore, chimeric enzymes with the N-terminal part from the human and the C-terminal part from the murine ... a chaperone or other factors influencing the formation of the active complex For example, it is possible that a protein in the 293-cells sequesters the Arg-containing subunits, thereby preventing...
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Báo cáo khoa học: Binding of ATP at the active site of human pancreatic glucokinase – nucleotide-induced conformational changes with possible implications for its kinetic cooperativity doc
... simulations of the modelled binary GK–ATP complex revealed that the global rmsd of the structure converged at the end of the 2-ns simulation period (Fig S2A) The dynamic changes in the active site ... 0.02 mM The data points and the solid line represent the difference between the WT and T228M hGK titrations (C) The same experiment as in (A), but performed on the GST fusion proteins The titration ... of these residues with the nucleotide at the active site The catalytic mechanism of GK has been the subject of several detailed analyses, and is still a partly unresolved issue Although some theoretical...
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Đề tài " Subelliptic SpinC Dirac operators, III The Atiyah-Weinstein conjecture " pot
... implies the uniqueness and therefore the invertibility of the model operators This completes the proof of Theorem We now turn to applications of these results eo Remark For the remainder of the paper ... of the symbol of the Calder´n o projector we need to compute the symbol along the contact direction This cA entails computing the contribution from q−2 As before, the terms arising from the ... shown that the order −1 term in the symbol of the Calder´n o projector, along the appropriate half of the contact line, is given by the righthand side of equation (83) It is determined by the principal...
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Báo cáo khoa học: Interactions of imidazoline ligands with the active site of purified monoamine oxidase A potx
... and the I2BS stereospecificities would be useful Interestingly, the lowest-energy orientation for each of the three ligands in the large active site of MAO-A put them in the middle of the active ... these I2BS ligands might be expected to bind in the active site in the same way as other reversible MAO-A inhibitors In the experiment in Fig 3, the extinction coefficient for guanabenz from the ... given in Table Evidence for the proximity of these ligands to the flavin in MAO-A comes from the influence of the ligand on the redox properties of the flavin Like other inhibitors of MAO-A [23,30],...
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Báo cáo khoa học: Site-directed mutagenesis of selected residues at the active site of aryl-alcohol oxidase, an H2O2-producing ligninolytic enzyme pot
... more than 50% of them clustered together in front of the rectus (re)-face of the isoalloxazine ring of the FAD cofactor This substrate location is shown in Fig 2A, which includes the 10 molecules ... nidulans, and the activities of the site-directed variants (when active) could be directly detected in filtrates of 48 h cultures of the transformants harbouring the mutated aao sequences The first ... with the hydroxyl group in Ca, representative of the range of AAO substrates [9,19,33] Most of these alcohols docked in front of the re-side of the isoalloxazine ring of FAD [34], with the benzylic...
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Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx
... that the carboxylic groups in the Asp140-Asp142-Glu144 triad contain two protons at the pH where the enzyme is most active The basic arm of the pH-activity profile must be determined by the loss ... in the preceding run Some of the pH profiles differed strongly from the wildtype profile, however, the profiles for the amide and corresponding alanine mutants were similar in all cases Together these ... the D140N, D142N, E144Q and D215N mutants, the pH-dependency of specific activity was recorded for these four mutants and the four corresponding alanine mutants The least active mutants (i.e the...
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